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Grand RoundsWeekly Evidence Brief

Family Medicine

Edition

30-Second Takeaway

  • Routine ADRD screening in primary care does not improve family caregivers’ quality of life, preparedness, or mental health.
  • A brief, multifaceted stewardship program can sharply reduce systemic steroid prescribing for acute respiratory infections in urgent care.
  • Organized invitations for oral exams dramatically increase screening and early lesion detection among high-risk tobacco users.
  • Simple scheduling changes, like protected video-only sessions, can reverse declining telehealth use in family medicine.
  • Health-related social needs in youth are tightly linked with obesity, smoking, and diabetes/prediabetes, supporting social risk screening.

Week ending April 25, 2026

Practical Updates for Family Physicians: Screening, Stewardship, Telehealth, Documentation, and Youth CVD Risk

Dementia Screening Offers No Measurable Benefit for Family Members in Primary Care

JAMA INTERNAL MEDICINEApr 21, 2026

In this 29-clinic randomized trial, 1808 older adult–family dyads were assigned to ADRD screening only, screening plus referral, or no screening. Only 5.1% of patients screened positive, and more than one-third of screen-positive patients in the referral arm declined diagnostic follow-up. At 24 months, family members’ SF-36 physical and mental scores were similar between combined screening and no-screening groups. Caregiver preparedness, caregiving self-efficacy, and depressive and anxiety symptoms were unchanged by screening. Patient quality-of-life and mood outcomes were also unaffected, suggesting minimal family benefit from routine ADRD screening in primary care.

Urgent Care Stewardship Substantially Reduces Steroid Prescribing for ARIs

JAMA NETWORK OPENApr 24, 2026

This quality-improvement study tested a steroid stewardship program for acute respiratory infections across 2 urgent care centers. Among 96 clinicians and 14,530 stewardship-eligible visits, mean systemic glucocorticoid prescribing fell from 20.4 to 8.8 per 100 visits. The program combined a brief virtual education, patient educational pamphlets, and peer-comparison email feedback with descriptive and injunctive norms. Interrupted time-series analysis showed a continued relative monthly prescribing rate reduction of 0.94 (95% CI, 0.92-0.96) during stewardship. Findings support low-touch outpatient stewardship interventions to curb unnecessary systemic steroids for uncomplicated ARIs.

Organized Oral Cancer Screening Greatly Expands Exams for High-Risk Smokers

INTERNATIONAL JOURNAL OF CANCERApr 21, 2026

This cluster-randomized trial in 35 Brazilian primary care units targeted adults ≥35 years who used tobacco and were high risk for oral cancer. Organized strategies using invitations plus either home visits or awareness campaigns achieved 77.2% preventive oral exam coverage versus 3.6% with opportunistic care. Adherence was higher with invitations plus community awareness (77.2%) than with invitations plus home-visit support (58.1%). Within organized arms, 15 biopsies identified 6 oral potentially malignant disorders and 5 oral cancers, with higher detection than biopsies outside the program. Results support structured, invitation-based oral exams in primary care to reach vulnerable smokers and detect lesions earlier.

ED-Initiated Video-Enhanced ACP Improves Documentation and Goal-Concordant Care

JOURNAL OF GENERAL INTERNAL MEDICINEApr 18, 2026

In this multicenter RCT, 598 older or seriously ill ED patients were randomized to video-enhanced ACP plus EHR notifications or usual care. At 3 months, ACP documentation was higher with the intervention (45.6% vs 31.3%; rate difference 14.3%, 95% CI 6.6%-22.0%). Benefits persisted at 6 months, and ACP knowledge and engagement scores were higher in the intervention group. Among 94 decedents, goal-concordant care scores were greater with the intervention (median 10 vs 7; P < .001). Brief, structured ACP workflows initiated during acute visits can increase documentation and better align end-of-life care with patient preferences.

References

Numbered in order of appearance. Click any reference to view details.

Additional Reads

Optional additional studies from this edition.

Edition context

Clinical signal

  • Limited downstream benefit and low follow-up rates weaken the rationale for routine ADRD screening aimed at helping family members.
  • Targeted education plus peer-comparison feedback is an effective, scalable approach to curb unnecessary steroid use for ARIs.
  • Risk-stratified, invitation-based oral cancer screening in primary care effectively reaches underserved smokers and finds more early lesions.