Urology

Author specialty predicts conclusions in nonrandomized RP vs RT studies

Review of 105 nonrandomized comparisons found 44% reported no difference, 42% favored radical prostatectomy, and 14% favored radiation. Multivariate analysis linked use of national databases (p = 0.01) and urology author specialty (p = 0.01) to conclusions favoring the author's specialty. Association persisted when excluding studies using only biochemical recurrence endpoints (urologist effect p = 0.006). These results imply specialty-driven interpretation of retrospective data and support multidisciplinary discussion when counseling about RP versus RT. 1

Knowledge gaps common in men with persistent postprostatectomy incontinence

Cross-sectional analysis of 526 men with PPI ≥12 months found 59% reported no knowledge of surgical incontinence treatment. Common barriers were satisfaction with pads (79%), concerns about surgical risks (53%), and doubts about efficacy (51%). Lower urine loss and missing information from clinicians independently predicted lack of knowledge (OR 2.4 and OR 4.2 respectively). Strengthening clinician-patient communication and providing guideline-based information may increase appropriate surgical uptake. 2

Consensus core outcome set for localized renal cell cancer (L-RCC-COS)

A three-phase Delphi and consensus process produced a 21-outcome core set for localized RCC trials and practice. The COS includes 10 universal outcomes and 11 intervention-specific outcomes to harmonize reporting and reduce research waste. Development involved 168 Delphi participants and consensus meetings with patients, clinicians, and researchers. Participants were Europe-based; external validation across languages and cultures is needed before global adoption. 3