Vascular Surgery

ciNPWT vs standard dressing for groin incisions after arterial surgery: no benefit

In a multicenter randomized trial of 275 patients with peripheral arterial disease, 25.5% had groin wound complications with no difference between ciNPWT (n=132) and standard dressing (n=143) (p=0.37). Time to complete wound healing and median hospital stay were similar between groups. Authors conclude routine ciNPWT is not recommended for groin incisions after peripheral arterial surgery. 1

Preoperative PCSK9 inhibitors associated with fewer 30‑day MACEs than statins

In a nationwide propensity‑matched cohort of 35,923 pairs, preoperative PCSK9 inhibitor use had lower 30‑day MACEs (6.4% vs 9.6%, NNT 31) versus statins. PCSK9 inhibitors were also associated with lower all‑cause mortality (RR 0.45), AKI, respiratory infections, delirium, and elevated liver enzymes. Results derive from observational data with propensity matching; randomized trials are needed before changing perioperative lipid management. 2

MySurgeryRisk accurately predicts ICU, MV, AKI, and mortality across centers

Across 508,097 encounters from 366,875 patients, MySurgeryRisk predicted ICU admission (AUROC 0.93), mechanical ventilation (0.94), AKI (0.92), and in‑hospital mortality (0.95). Primary procedure code and clinician‑specific factors were the most influential predictors. Model performance held across temporal validation but local recalibration is prudent before clinical deployment. 3